This Medudy course is a video tutorial for physicians on the topic of “PNH in Everyday Clinical Practice.”
In this video, Dr. Jörg Chromik, senior physician and director of the Hematology and Oncology Outpatient Clinic at Frankfurt University Hospital, discusses paroxysmal nocturnal hemoglobinuria (PNH) and its significance in everyday clinical practice.
This first video in a series on PNH, an acquired disorder of the hematopoietic stem cells, focuses on the most important warning signs and symptoms. After a brief discussion of the epidemiology, the mostly nonspecific and variable symptoms are described, and the video explains why it is so important to be able to recognize warning signs and interpret clinical presentations even in other medical specialties. Finally, the video briefly explains the recommended course of action when PNH is suspected.
Note: All “speakers” appearing in the Medudy videos are AI-based avatars used to enhance the educational value of the videos. The individuals on whom the avatars are based have explicitly consented to their use. The video’s content was created and reviewed by the editorial team with the aid of AI, based on high-quality scientific sources, and has been approved by the speakers.
This course was created with the kind support of Sobi.
By the end of this course, you will know:
- The epidemiology and clinical presentation of PNH
- the nonspecific and variable symptoms of PNH
- The most important warning signs of possible PNH
- Next Steps If PNH Is Suspected


