This Medudy Expert Opinion with Prof. Sherko Kümmel is a video tutorial for physicians on the topic "Practical tips for dealing with side effects of immunotherapy in triple-negative breast cancer".
A comparison is made between the side effect profiles of chemotherapy and immunotherapy, emphasizing the higher variability and the involvement of different organ systems under immunotherapy. The administration of immunotherapy can lead to immune-associated side effects (irUE), the early recognition of which is essential. The time course of side effects is highly variable, and they can occur even months after the end of therapy.
Note: All "speakers" appearing in the Medudy videos are AI-based avatars used to improve the didactics of the videos. The people on whom the avatars are based have explicitly consented to their use. All content is based on high-quality scientific sources and is created and reviewed by the Medudy medical team.
The course was created with the kind support of Gilead Science and MSD.
At the end of this training you will know:
- the differences in the side effect profile and time course between chemotherapy and immunotherapy in triple-negative breast cancer (TNBC)
- the concept of immune-mediated adverse events (irUE) and the need for early detection and consistent treatment, including the use of corticosteroids
- the most frequently affected organ systems and the broad variability of possible organ-specific irUE under immune checkpoint inhibitors
- the typical but generally variable time course of the occurrence of immune-mediated side effects, which can occur even months after the end of treatment
